Rakesh Kumar, MD
Dr. Rakesh Kumar has been taking care of patients with kidney disease, hypertension, electrolytes abnormalities, and kidney stones since 2012. He has a special interest in treating patients with hypertension, glomerular disease, acute kidney injury, and electrolyte abnormalities. He emphasizes quality care and patient satisfaction. He has research experience in basic science as well as in clinical research. He has authored several research articles in reputed peer-reviewed journals and has presented at National meetings.
Renal physiology has remained his most interesting subject since medical school. Its complexity has always fascinated him. Kidney disease is associated with many other organ diseases directly, or indirectly, which makes it very challenging. He enjoys all aspects of nephrology.
1) The Macrophage Mediates the Renoprotective Effects of Endotoxin Preconditioning
Takashi Hato, Seth Winfree, Rabih Kalakeche, Shataakshi Dube, Rakesh Kumar,
Momoko Yoshimoto, Zoya Plotkin, and Pierre C. Dagher
Journal of American Society of Nephrology 26, doi: 10.1681/ASN.2014060561, 2015
2) Interventions to Reduce Clinical Inertia in Cardiac Risk Factor Management in Renal Transplant Recipients
Dhanashri D. Kohok, Silvi Shah, Rakesh Kumar, Lisa Venuto, Gregory Gudleski, Rocco Venuto
The Journal of Clinical Hypertension Vol 16, No 2, February 2014
3) Comparison of 12 hours Creatinine Clearance and Estimated Glomerular Filtration Rate in Renal Transplant Recipients
Rakesh Kumar, Prashant Pendyala, Kris Attwood, Vanessa Gray, Rocco Venuto, Kathleen Tornatore.
Renal Failure, Volume 35 Issue 3, March 2013.
4) Assessment of Cardiovascular Risk Factors after Renal Transplantation – A Step towards Reducing Graft Failure
Rakesh Kumar, Jyoti Brar, Rabi Yacoub, Talal Khan, Mareena Zachariah, Rocco Venuto. Transplant Proc. 2012 Jun;44(5):1270-4 PMID 22663999.
5) Effect of steroid-free, low concentration calcineurin inhibitors maintenance immunosuppression regimen on renal allograft histopathology and function
Nainani N, Patel N, Tahir N, Kumar R, Weber-Shrikant E, Gundroo AA, Murray BM, Tornatore KM, Blessios GA, Venuto RC. Nephrol Dial Transplant. 2011 Nov 5; 20111107 (1460-2385 Electronic)
6) Evaluation of the D3 dopamine receptor selective agonist/partial agonist PG01042 on l-dopa dependent animal involuntary movements in rats
Riddle LR, Kumar R, Griffin SA, Grundt P, Newman AH, Luedtke RR. Neuropharmacology. 2011;60(2–3):284-294.
7) Evaluation of D2 and D3 dopamine receptor-selective compounds on L-dopa-dependent abnormal involuntary movements in rats
Rakesh Kumar, Lindsay R. Riddle , Suzy A. Griffin , Wenhua Chu, Suwanna Vangveravong,Janet Neisewander , Robert H. Mach, Robert R. Luedtke.
Neuropharmacology. 2009 May-Jun;56(6-7):956-69. Epub 2009 Feb 5.
8) Evaluation of the D3 dopamine receptor selective antagonist PG01037on L-dopa-dependent abnormal involuntary movements in rats
Rakesh Kumar, Lindsay Riddle, Suzy A. Griffin, Peter Grundt, Amy Hauck Newman, Robert R. Luedtke
Neuropharmacology. 2009 May-Jun;56(6-7):944-55. Epub 2009 Feb 5.
9) N-(4-(4-(2,3-Dichloro- or 2-methoxyphenyl)piperazin-1-yl)butyl) heterobiarylcarboxamides with Functionalized Linking Chains as High Affinity and Enantioselective D3 Receptor Antagonists
Newman AH, Grundt P, Cyriac G, Deschamps JR, Taylor M, Kumar R, Ho D, Luedtke RR. J Med Chem. 2009 Apr 23; 52(8): 2559-70.
10) Structure-activity relationships for a novel series of dopamine D2-like receptor ligands based on N-substituted 3-aryl-8-azabicyclo [3.2.1] octan-3-ol.
Paul NM, Taylor M, Kumar R, Deschamps JR, Luedtke RR, Newman AH.
J Med Chem. 2008 Oct 9; 51(19): 6095-109. Epub 2008 Sep 6.
11) Inhibition of Toll-Like Receptor 4 Signaling Mitigates Microvascular Loss but Not Fibrosis in a Model of Ischemic Acute Kidney Injury
Pierre C. Dagher, Takashi Hato, Henry E. Mang, Zoya Plotkin, Quentin V. Richardson, Michael Massad, Erik Mai, Sarah E. Kuehl, Paige Graham, Rakesh Kumar, and Timothy A. Sutton
International Journal of Molecular Sciences. 2016 May; 17(5): 647.
American Society of Nephrology 2013
Myeloid Cells Are Essential Mediators of Renal Endotoxin Preconditioning
Takashi Hato, Rakesh Kumar, Pierre C. Dagher
American Transplant Congress, Philadelphia, 2011
Cardiovascular risk factors in renal allograft recipients – experience at university based transplant clinic
Rakesh Kumar, MBBS, Rabi Yacoub, MD, Talal Khan , MBBS, Jyoti Brar, MBBS, Mareena Zachariah, MD, Rocco Venuto, MD.
1) American Society of Nephrology, San Diego 2012
Interventions to Reduce Clinical Inertia in Cardiac Risk Factor Management in Renal Transplant Recipients
Dhanashri Kohok, MBBS, Silvi Shah, MBBS, Rakesh Kumar, MBBS, Gregory Gudleski, PhD, Rocco Venuto, MD.
2) American Transplant Congress, Philadelphia, 2011
Alemtuzumab (C-1H) Induction and Prednisone-Free Maintenance Immunotherapy in Kidney Transplantation Compared with Rabbit Anti-Thymocyte Globulin (rATG) Induction with Steroid Maintenance: Long-Term Results.
M. Zachariah, N. Nader, R. Kumar, T. Khan, R. Yacoub, M. Panesar, R. Venuto, M. Laftavi, O. Pankewycz.
3) National Kidney Foundation Spring Meeting, Las Vegas, 2011
Intradialytic Parenteral Nutrition: Effect on Albumin and Normalized Protein Catabolic Rate.
Kumar R, Dogra P, Kohok D, Pratt L , Pinzone A, Sridhar NR.
American Journal of Kidney Diseases. 2011 Apr; Volume 57(Issue 4): Page B55.
4) American College of Physicians New York Chapter 2010 Meeting (Second Prize in Research Category):
Hypertension and Hyperlipidemia in Renal Transplant Patients – Experience at University-Based Transplant Clinic.
Rakesh Kumar, Rabi Yacub, Talal Khan, Jyoti Brar, Mareena Zachariah, and Rocco C. Venuto.
5) Research Appreciation Day 2008- UNTHSC
Pharmacological Evaluation of D2 like Dopamine Receptor Selective Compounds On L-Dopa Induced Dyskinesias In Parkinson’s Disease
Rakesh Kumar, Michelle Taylor, Lindsay Riddle, Suzy A. Griffin, Peter Grundt, Amy Newman, and Robert R. Luedtke.
6) Behavior, Biology, and Chemistry [BBC] Conference sponsored by NIDA San Antonio, 2010.
Design and synthesis of N-(3-fluoro-4-(4-(2,3-dichloro or 2-methoxyphenyl) piparazine-1-yl)-butyl)-heterobiaryl and biaryl carboxamides as selective dopamine D3 receptor ligands.
Kumar R, Taylor M, Luedtke RR, Newman AH.
7) Keystone Symposium Structural Biology and Activation Mechanism of membrane Receptors Cambridge UK 2008
Evaluation of D3 dopamine receptor-selective compounds on L-dopa induced abnormal involuntary movements and apomorphine-dependent attenuation of prepulse inhibition in rats.
Luedtke RR, Kumar R, Griffin SA, Weber M, Chu W, Swerdlow N, and Mach RH.
8) Soc Neurosci Abst. Washington D.C. 2008
Structure-activity relationships (SAR) for tropine and bridged-piperazine containing dopamine D2-like receptor ligands.
Paul NM, Taylor M. Kumar R, Luedtke RR and Newman AH.
9) Soc Neurosci Abst. Washington D.C. 2008
Pharmacological evaluation of the D2 and D3 dopamine receptor-selective compounds on L-dopa dependent animal involuntary movements in rats.
Luedtke RR, Kumar R, Griffin SA, Chu W, Mach RH.
10) Soc Neurosci Abst. Washington D.C. 2008
Evaluation of the D3 dopamine receptor selective antagonist PG01037 on L-dopa dependent abnormal involuntary movements in rats.
Griffin SA, Kumar R, Riddle L, Grundt P, Newman AH and Luedtke RR.
Grand Round Presentations at Indiana University
- Lithium and its Nephrotoxicity
- Polycystic Kidney disease
- Salt and Hypertension
CME Presentation at Union Hospital, Terre Haute, Indiana
- Acute renal failure
- Internal Medicine
University at Buffalo, NY
B.J Medical College, Pune, India
- American College of Physicians
- American Society of Nephrology
- 2010 Arnold P. Gold Foundation Humanism and Excellence in Teaching Award for Outstanding Resident Role Model given by University at Buffalo School of Medicine and Biomedical Sciences.,
- Zebra Award 2008 for rare case diagnosis by East Tennessee State University Family Medicine Program Kingsport, TN.,
- American College of Physicians New York Chapter Poster Session- Second position in the research category.
Additional areas of clinical expertise, training, subspecialty certifications, or interests
- Master of Science (Pharmacology and Neuroscience)
- UNT Health Science Center, Fort Worth, Texas